Reina Ramierez is Nikki's older sister and Manny Maladero's partner.
Reina Ramierez is an straight A student at Santo Juan Academy, and she is proficient at using many weapons, gadgets, and disguises.
She has wide, green eyes and pale skin. She has long red hair. Reina usually wears a black dress shirt with a black skirt, a brown leather jacket, black combat boots and carries a black backpack.
Reina is the quiet type and speaks only when necessary, she maintains a rather goth aura (judging by her clothes). Although quiet, Reina is caring and determined, and is Manny's best friend.
- My Baby Sister's a Reaper (English) - Grey DeLisle
- 'Mi hermanita es una parca'(Latino Spanish) - Claudia Chavarro